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Table 1 MT-I+II, MT-III, IL-6 mRNAs and zinc content in the thymus from young, old and very old mice.

From: Are zinc-bound metallothionein isoforms (I+II and III) involved in impaired thymulin production and thymic involution during ageing?

Mice

MT-I+II (MT-I/βactin)

IL-6 (IL-6/βactin)

MT-III (MT-III/βactin)

Zinc content (μg/gr.)

Absolute thymus weight (mg)

Young

0.18 ± 0.02

0.14 ± 0.03

0.48 ± 0.02

62.3 ± 11.2

30.6 ± 5.0

Old

3.52 ± 0.3*

0.23 ± 0.02§

1.65 ± 0.03*

107.4 ± 27.5**

13.6 ± 2.0§

Very old

1.29 ± 0.6+

0.18 ± 0.04+

1.63 ± 0.02*

77.4 ± 8.7

15.4 ± 2.3§

  1. *p < 0.001 when compared to young mice; +p < 0.01 when compared to old mice;
  2. **p < 0.01 when compared to young and very old mice; §p < 0.01 when compared to young mice;
  3. ++p < 0.05 when compared to old mice
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Immunity & Ageing

ISSN: 1742-4933

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