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Fig. 9 | Immunity & Ageing

Fig. 9

From: Rapamycin, Acarbose and 17α-estradiol share common mechanisms regulating the MAPK pathways involved in intracellular signaling and inflammation

Fig. 9

Effect of a p38MAPK inhibitor on the expression of Acute Phase Proteins in AML-12 cells. A Right panel shows effects of 48 h treatment with Doramapimod (Dor, p38MAPK inhibitor) on pMK2, MK2 protein levels, p-p38 levels and p38 protein levels. Middle panel shows the mean ± SEM for pMK2 and MK2 (Short and Long isoforms), p-p38 and p38 from 6 independent experiments. Right panels show the effects on mRNA levels for these proteins. B Effects of Dor on SAP, HMOX2 and Cas6 from the samples described above. The (*) indicates statistical significance (p < 0.05) in a t-test between the indicated pair of groups

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Immunity & Ageing

ISSN: 1742-4933

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