Fig. 8
From: Single-cell landscape of immunological responses in elderly patients with sepsis
Metabolism-associated pathways enriched of T cells in the elderly with sepsis A, The GSEA enrichment plot showing the selected enriched genesets in KEGG pathway of T cells in E-SEP versus Y-SEP groups. And color-coded by normalized enrichment score. B, The GSEA NES heatmap of the enriched metabolism-associated genesets in KEGG pathway of T cells in E-SEP versus Y-SEP, E-SEP versus E-NoSEP, E-SEP versus Control, and Y-SEP versus Control. Red represents upregulated in the former group, and blue represents downregulated in the former group, respectively. C, Bubble plots showing the enriched metabolism-associated genesets in KEGG pathway of seven T cell subsets. Comparisons between two different conditions are shown in different colors, while orange indicates the comparison between E-SEP and Y-SEP. The dot size represents normalized enrichment score. D, Dot plots showing the expression of genes that involved in the lysine degradation pathway across four conditions. The color key from blue to red indicates low to high expression levels. The dot size indicates the percentage of cells that expresses genes