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Fig. 2 | Immunity & Ageing

Fig. 2

From: Monocyte-driven inflamm-aging reduces intestinal barrier function in females

Fig. 2

Age-associated inflammation is altered by biological sex. Simple linear regression showing a significant age-associated increase in the chemokines (A) IL-8 and (B) CXCL10 in both sexes. Females had an increase in circulating (C) TNF, (D) VEGF-A and (E) CRP with age. (F) Although no changes in IL-10 occurred, (G) there was an increase in the TNF to IL-10 ratio in females with age. (H) Males had higher overall TNF levels, but unlike in the females, these levels did not change with age. Statistical significance was assessed by a Student’s t test. *P ≤ 0.05

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Immunity & Ageing

ISSN: 1742-4933

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