Table 2 Whole-blood myeloid cell prevalence by biological sex and chronological age

% CD45⁺leukocytes

Monocytes

Male

3.7(2.16)

3.77(1.8–5.5)

3.8(1.6)

4.11(3.1-5.0)

5.4(2.2)

4.58(3.9–6.4)

Female

2.8(1.5)

2.5(2-3.8)

4.36(1.51)

4.5(3-5.6)

4.4(1.5)

4.2(3.6–5.3)

Classical monocytes

Male

3.4(2.1)

3.6(1.17–4.99)

3.49(1.56)

3.9(3-4.7)

5.02(1.98)

4.1(3.7–6.1)

Female

2.5(1.49)

2.23(1.8–3.4)

3.96(1.4)

4.15(2.7–5.2)

4.11(1.4)

3.8(3.2–5.1)

Intermediate monocytes

Male

0.15(0.16)

0.10(0.03–0.27)

0.17(0.13)

0.15(0.06–0.25)

0.19(0.12)

0.18(0.07–0.25)

Female

0.16(0.12)

0.15(0.06–0.23)

0.18(0.2)

0.12(0.06–0.21)

0.15(0.11)

0.11(0.09–0.16)

Non-classical monocytes

Male

0.11(0.07)

0.11(0.04–0.19)

0.14(0.07)

0.15(0.07–0.2)

0.14(0.08)

0.14(0.07–0.19)

Female

0.12(0.07)

0.12(0.06–0.19)

0.10(0.07)

0.07(0.05–0.12)

0.16(0.11)

0.15(0.06–0.24)

% Monocytes

Classical monocytes

Male

86.1(14.3)

94.4(71–97)

87.9(11.1)

92.1(86–95)

93.1(3.2)

93.3(90–96)

Female

86.4(10.2)

89.9(76–92)

92.6(5.0)

94.2(88–96)

92.05(4.47)

92.8(89–94)

Intermediate monocytes

Male

6.0(7.6)

2.2(0.79–10.6)

5.22(3.6)

4.2(1.7–8.5)

3.4(1.9)

3.0(1.9–4.4)

Female

7.3(6.2)

5.4(2.6–10.5)

4.4(3.4)

3.8(1.6–6.5)

3.6(2.7)

2.9(1.9–3.5)

Non-classical monocytes

Male

5.5(6.3)

1.5(1.2–12.1)

5.3(6.4)

3.2(1.9–5.1)

3.0(1.6)

2.6(1.8–4.6)

Female

4.5(3.1)

3.1(2.1–7.9)

2.6(2.4)

1.8(1.3–3.1)

3.7(2.4)

3.5(1.9–4.7)

Correlations by chronological age

Variables

Beta

Std. Error

R²

P

% CD45⁺leukocytes

Monocytes

Male

0.038

0.01

0.17

0.006*

Female

0.02

0.009

0.10

0.01*

Classical monocytes

Male

0.036

0.012

0.172

0.006*

Female

0.023

0.005

0.11

0.01*

Intermediate monocytes

Male

0.001

0.0009

0.033

0.24

Female

0.0001

0.0009

0.0007

0.84

Non-classical monocytes

Male

0.000

0.000

0.01

0.49

Female

0.001

0.0005

0.07

0.04*

% Monocytes

Classical monocytes

Male

0.14

0.07

0.09

0.05*

Female

0.05

0.03

0.04

0.14

Intermediate monocytes

Male

-0.03

0.03

0.04

0.20

Female

-0.04

0.02

0.06

0.06

Non-classical monocytes

Male

-0.05

0.03

0.06

0.11

Female

-0.0007

0.01

0.00

0.96