Table 3 Whole-blood myeloid cell numbersa by biological sex and chronological age
From: Monocyte-driven inflamm-aging reduces intestinal barrier function in females
|  | Sex | Young adult (n = 8 M; 9 F) | Adult (n = 20 M; 21 F) | Older adult (n = 13 M; 24 F) | |||
|---|---|---|---|---|---|---|---|
Mean (SD) | Median (IQR) | Mean (SD) | Median (IQR) | Mean (SD) | Median (IQR) | ||
Cell population | Â | Â | Â | Â | Â | Â | Â |
Monocytes | Male | 103.1(79.2) | 93.2(31–183) | 113.7(79.6) | 100.5(42–180) | 127.3(109.) | 93.6(60–137) |
|  | Female | 54.3(38.4) | 50.3(24–68) | 107.8(81) | 98.1(62–129) | 109.3(77.6) | 84.9(52–150) |
Classical monocytes | Male | 100.5(80.29) | 128.8(20–181) | 106.2(78.0) | 91.5(35–179) | 119.2(106) | 85.6(56–164) |
|  | Female | 48.9(38.4) | 47.2(19–60) | 98.1(72.9) | 94.3(37–119) | 101.6(74.0) | 77.9(49–140) |
Intermediate monocytes | Male | 3.6(2.8) | 2.8(1-6.9) | 4.8(3.8) | 3.7(2.8–6.5) | 4.0(3.1) | 3.9(1.1–6.2) |
|  | Female | 2.7(1.7) | 2.0(1.6–4.3) | 5.4(6.5) | 3.1(1.9–5.9) | 3.4(2.4) | 2.6(1.4–5.4) |
Non-classical monocytes | Male | 2.7(1.1) | 2.7(1.9–3.2) | 3.8(2.1) | 4.1(1.5–5.6) | 3.5(3.2) | 3.1(1.5–4.7) |
| Â | Female | 2.3(1.6) | 2.0(1.5-3.0) | 3.1(3.4) | 1.9(1.0-3.4) | 3.7(2.7) | 3.1(1.3-5.0) |
Correlations by chronological age | Â | Â | Â | Â | Â | Â | |
Variables | Â | Â | Beta | Std. Error | R2 | P | Â |
Monocytes | Male | Â | 0.25 | 0.64 | 0.004 | 0.69 | Â |
| Â | Female | Â | 1.03 | 0.45 | 0.09 | 0.02* | Â |
Classical monocytes | Male | Â | 0.16 | 0.66 | 0.001 | 0.8 | Â |
| Â | Female | Â | 0.98 | 0.42 | 0.09 | 0.02* | Â |
Intermediate monocytes | Male | Â | -0.003 | 0.02 | 0.001 | 0.90 | Â |
| Â | Female | Â | -0.004 | 0.02 | 0.001 | 0.86 | Â |
Non-classical monocytes | Male | Â | -0.01 | 0.01 | 0.003 | 0.72 | Â |
| Â | Female | Â | 0.03 | 0.02 | 0.07 | 0.048* | Â |