Fig. 2

Kaplan–Meier survival curves based on IgM, IgG, IgA, and LnIgE, grouped into quartiles. The Kaplan–Meier survival curves revealed significant associations between higher IgM levels and increased survival time. The median survival time was significantly shorter for participants in the Q1 group than Q4 group on the serum IgM group (26 months versus 33 months, P = 0.003) (A). The median survival time was significantly shorter for participants in the Q1 group than Q2-Q4 group on the serum IgM group (26 months versus 32 months, P = 0.001) (B). Kaplan–Meier survival curves revealed associations between higher IgG levels and decreased survival time. The median survival time was shorter for individuals in the Q4 group than Q1 group on the serum IgG group (26 months versus 35 months, P = 0.013) (C). The median survival time did not significantly differ based on IgA and LnIgE levels (D, E)