Fig. 4

Log2 fold-change (LFC) in antibody concentrations corrected for baseline concentrations and stratified by infection status. Significant associations are shown in red. The intercept shown in the figure refers to the intercept of the fitted regression model. For primary vaccination AZD1222 was taken reference, whereas for first and second booster BNT162b2 was compared with mRNA-1273 as reference. A negative Beta refers to a smaller LFC which can either refer to a weaker increase upon vaccination or a stronger (more negative) decrease thereafter. Separate multivariable linear regression results are shown for A) baseline characteristics, B) cardiometabolic markers, and C) comorbidities