Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.

You are viewing the site in preview mode

Skip to main content
Fig. 10 | Immunity & Ageing

Fig. 10

From: Elocalcitol mitigates high-fat diet-induced microglial senescence via miR-146a modulation

Fig. 10

Elocalcitol reduces HFD-induced senescence and SASP cytokines in liver of WT mice but not Mir146a-/- mice. (A) qPCR analysis of p21 mRNA expression levels, (B) Relative mRNA expression of Il18, (C) Tnf, and (D) Il6 in the liver, analyzed by RT-qPCR with primers for the indicated genes in the liver. Number of animals = 4–5. Data in panels (A-C) did not show normal distribution and were transformed into logarithms (Y = log(Y) and further processed using one-way ANOVA with Tukey’s multiple comparisons test and (D) was analyzed using two-way ANOVA followed by Tukey’s multiple comparisons test. Data are represented as mean ± SEM; * p < 0.05, ** p < 0.01

Back to article page

Immunity & Ageing

ISSN: 1742-4933

Contact us