Fig. 2

Mean fluorescence intensity of Sestrin-2, granzyme B, and Ki-67 across CD8+ T cells maturation stages. The mean fluorescence intensity (MFI) of Sestrin-2, granzyme B, and Ki-67 was measured across different stages of CD8 + T cell maturation, ranging from the least differentiated (naïve) to the most differentiated (CD57 + DAP12 + EMRA) cells (n = 35). CM: central memory; EM: effector memory. Differences between the two groups were tested using a two-sided unpaired t-test. The p-values are indicated by asterisks as follows: < 0.05*, < 0.01**, < 0.001***, < 0.0001****