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Fig. 2 | Immunity & Ageing

Fig. 2

From: CD57+ EMRA CD8+ T cells in cancer patients over 70: associations with prior chemotherapy and response to anti-PD-1/PD-L1 therapy

Fig. 2

Mean fluorescence intensity of Sestrin-2, granzyme B, and Ki-67 across CD8+ T cells maturation stages. The mean fluorescence intensity (MFI) of Sestrin-2, granzyme B, and Ki-67 was measured across different stages of CD8 + T cell maturation, ranging from the least differentiated (naïve) to the most differentiated (CD57 + DAP12 + EMRA) cells (n = 35). CM: central memory; EM: effector memory. Differences between the two groups were tested using a two-sided unpaired t-test. The p-values are indicated by asterisks as follows: < 0.05*, < 0.01**, < 0.001***, < 0.0001****

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