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Table 2 Overall response rate and mortality according to CD57+EMRA CD8+ T cell positivity

From: CD57+ EMRA CD8+ T cells in cancer patients over 70: associations with prior chemotherapy and response to anti-PD-1/PD-L1 therapy

Outcome

Available data

Total n=35

CD57+EMRA< 10 n= 16

D57+EMRA ≥ 10 n= 19

ORR at 6 months

29

   

Complete response

 

0

0

0

Partial response

 

6/29 (21%)

3/12 (25%)

3/17 (18%)

Stable disease

 

5/29 (17%)

2/12 (17%)

3/17 (18%)

Progressive disease

 

6/29 (21%)

1/12 (8%)

5/17 (29%)

Death

 

12/29 (41%)

6/12 (50%)

6/17 (35%)

Global death

35

23/35

11/17

12/17

  1. The 6-month overall response rate and mortality are shown for the entire population and stratified by CD57+ EMRA positivity (using a 10% cut-off among CD8+ T cells)