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Fig. 1 | Immunity & Ageing

Fig. 1

From: scRNA + BCR-seq identifies proportions and characteristics of dual BCR B cells in the peritoneal cavity of mice and peripheral blood of healthy human donors across different ages

Fig. 1

Analysis of Heavy and Light Chain Expression in Single B Cells Reveals Diversity of Peritoneal B Cells. (A) Identification of B cells expressing multiple heavy (H) and light (κ and λ) chains by single-cell analysis. (B) Classification of peritoneal B cells into six types based on BCR heavy and light chain pairing in mice aged 6 days, 10 weeks, and 15 months. (C) Decrease in H + κ and H + λ B cells and increase in dual κ chain-expressing B cells in elderly mice. (D) Increase in dual BCR B cells in elderly mice compared to 6-day-old and 10-week-old mice

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Immunity & Ageing

ISSN: 1742-4933

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