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Fig. 2 | Immunity & Ageing

Fig. 2

From: Chronic IL-21 drives neuroinflammation and promotes lipid accumulation in microglia

Fig. 2

IL-21 activates microglia and promotes lipid accumulation within these cells. Mice were injected with IL-21 twice weekly for total of 5 injections. The activation of microglia and lipid accumulation in microglia was determined by flow cytometry. Dot plots depict the MFI of- (A) MHC-II; (B) CD68; (C) BODIPY; (D) CD36; (E) TREM-2 on CD45 + CD11b + gated microglia. Data is Mean +/- S.E

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